Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Vessel tone and remodeling

Nature Medicine volume 12, pages 16–17 (2006)Cite this article

Changes in blood flow and hypoxia lead to endothelial-mediated control of vascular tone. An additional nucleotide receptor on endothelial cells has been identified that mediates release of nitric oxide and vasodilation (pages 133–137).

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Purines and pyrimidines control vascular tone through P2 receptors.

References

  1. Yamamoto, K. et al. Nat. Med. 11, 133–137 (2005).

    Google Scholar 

  2. Burnstock, G. & Ralevic, V. Br. J. Plast. Surg. 47, 527–543 (1994).

    Article  CAS  Google Scholar 

  3. Burnstock, G. Arterioscl. Throm. Vas. Biol. 22, 364–373 (2002).

    Article  Google Scholar 

  4. Ralevic, V. & Burnstock, G. Pharmacol. Rev. 50, 413–492 (1998).

    CAS  PubMed  Google Scholar 

  5. Burnstock, G. Curr. Topics Medic. Chem. 4, 793–803 (2004).

    Article  CAS  Google Scholar 

  6. Burnstock, G. Neurochem. Int. 17, 357–368 (1990).

    Article  CAS  Google Scholar 

  7. Burnstock, G. J. Anat. 194, 335–342 (1999).

    Article  CAS  Google Scholar 

  8. Ralevic, V. Handbook of Experimental Pharmacology Vol. 151/II. Purinergic and Pyrimidinergic Signalling II - Cardiovascular, Respiratory, Immune, Metabolic and Gastrointestinal Tract Function (eds. Abbracchio, M.P. & Williams, M.) 151 (Volume II), 101–120 (Springer, 2001).

    Google Scholar 

  9. Wang, L. et al. J Cardiovasc. Pharmacol. 40, 841–853 (2002).

    Article  CAS  Google Scholar 

  10. Ray, F.R. et al. Atherosclerosis 162, 55–61 (2002).

    Article  CAS  Google Scholar 

  11. Harrington, L.S. & Mitchell, J.A. Br. J Pharmacol. 143, 611–617 (2004).

    Article  CAS  Google Scholar 

  12. Ralevic, V. & Burnstock, G. Drug News Perspect. 16, 133–140 (2003).

    Article  CAS  Google Scholar 

  13. Jacobson, K.A. et al. Novartis Foundation Symposium 276 Purinergic Signalling in Neuron-Glial Interactions (John Wiley & Sons, Ltd., in the press).

Download references

Author information

Authors and Affiliations

  1. Autonomic Neuroscience Centre, Royal Free & University College Medical School, London, NW3 2PF, UK

    Geoffrey Burnstock

Authors
  1. Geoffrey Burnstock
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Burnstock, G. Vessel tone and remodeling. Nat Med 12, 16–17 (2006). https://doi.org/10.1038/nm0106-16

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm0106-16

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing