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Setting the cytokine trap for autoimmunity

Agents that block the action of specific cytokines have changed the lives of many patients with rheumatoid arthritis and other autoimmune disorders. But frequent self-injections or injections by a physician during a clinic visit are required. Now a new class of anti-cytokine that may bypass such problems appears on the horizon (pages 47–52).

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Figure 1: Blocking IL-1 activity.
Figure 2: Cytokine trap treats inflammation in arthritic mice.

Courtesy of E. Koehler-Stec, T. Sterlacci and S. Staton

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Dinarello, C. Setting the cytokine trap for autoimmunity. Nat Med 9, 20–22 (2003). https://doi.org/10.1038/nm0103-20

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