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Pten-uating neural growth

Nature Medicine volume 8, pages 16–18 (2002)Cite this article

Conditional deletion of the Pten tumor suppressor gene in the nervous system demonstrates that Pten is an important regulator of proliferation in neural stem cells and soma size in neurons.

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Figure 1: In mice, Pten deficiency leads to increased proliferation and increased cell survival in neural progenitors and to increased soma growth in postmitotic neurons.

Renee Lucas

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  1. Howard Hughes Medical Institute and Departments of Internal Medicine and Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA

    Sean J. Morrison

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  1. Sean J. Morrison
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Morrison, S. Pten-uating neural growth. Nat Med 8, 16–18 (2002). https://doi.org/10.1038/nm0102-16

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  • DOI: https://doi.org/10.1038/nm0102-16

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