The Biopolis complex in Singapore is both an inspiring and daunting place to do a postdoc. The motto for the complex of nine glass buildings erected within the past seven years is “racing with the world's best towards the very limits of modern science”. These ambitions clash spectacularly with the mundane realities of lab work. As a postdoctoral fellow there, I am acutely aware of this stark contrast between dream and reality. It weighs heavily on me as I attempt to chart my course through a new year fraught with uncertainty.

Furthermore, how do I adapt to the local working environment? Research is not done in a vacuum — everyone makes a difference, whether administrative staff, a lab technician or the 'big boss'. Having been educated in the United States, I notice many differences, such as in communication style, approach to project management and work ethic. The highly structured and hierarchical nature of an Asian workplace contrasts with the collegial atmosphere of a US academic institution, and personal interactions differ accordingly. Figuring out how to respond and adapt is important in our international community.

The new year will bring many changes and promises to be challenging at many different levels. I have to remain focused and positive, and hope to emerge a better scientist and person.