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Bringing age-related macular degeneration into focus

Genetic studies of age-related macular degeneration (AMD), the most prevalent blinding condition among the elderly, have had both great success and deep controversy. A new study now begins to resolve contradictory views over two candidate genes at a major AMD locus on chromosome 10q26 by suggesting a functional variant in one of these genes.

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Figure 1: Genes and variants in the 10q26 locus.

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Allikmets, R., Dean, M. Bringing age-related macular degeneration into focus. Nat Genet 40, 820–821 (2008). https://doi.org/10.1038/ng0708-820

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