Pigmentation traits are known risk factors for skin cancer. Now, three new studies provide insights into the genetic factors underlying these effects, and the results reveal a surprisingly complex picture of the relationship between pigmentation traits and disease risk.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
McCarthy, M.I. et al. Nat. Rev. Genet. 9, 356–369 (2008).
Manolio, T.A., Brooks, L.D. & Collins, F.S. J. Clin. Invest. 118, 1590–1605 (2008).
Gudbjartsson, D.F. et al. Nat. Genet. 40, 835–837 (2008).
Brown, K.M. et al. Nat. Genet. 40, 838–840 (2008).
Sulem, P. et al. Nat. Genet. 40, 886–891 (2008).
Sulem, P. et al. Nat. Genet. 39, 1443–1452 (2007).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Pharoah, P. Shedding light on skin cancer. Nat Genet 40, 817–818 (2008). https://doi.org/10.1038/ng0708-817
Issue Date:
DOI: https://doi.org/10.1038/ng0708-817
This article is cited by
-
Mutations in ERBB4 May Have a Minor Role in Melanoma Pathogenesis
Journal of Investigative Dermatology (2013)
-
Direct migration of follicular melanocyte stem cells to the epidermis after wounding or UVB irradiation is dependent on Mc1r signaling
Nature Medicine (2013)