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A bird's eye view of global methylation

Nature Genetics volume 24, pages 101–102 (2000)Cite this article

Abstract

Restriction landmark genomic scanning applied to a broad variety of cancer types can disclose tumour-specific and tumour-type–specific global methylation profiles. This and other genome-scanning approaches allows the rapid analysis of methylation profiles of thousands of genes in parallel—and promises to identify new genes critical to carcinogenesis and other biological processes.

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Author information

Authors and Affiliations

  1. Clinical Cancer Genetics Program, Ohio State University Comprehensive Cancer Center, Columbus, 43210, Ohio, USA

    Charis Eng

  2. Cancer Research Campaign Human Cancer Genetics Research Group, University of Cambridge, Cambridge, CB2 2QQ, UK

    Charis Eng

  3. The Johns Hopkins Comprehensive Cancer Center and Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, 21231, Maryland, USA

    James G Herman & Stephen B Baylin

Authors
  1. Charis Eng
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  2. James G Herman
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  3. Stephen B Baylin
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Eng, C., Herman, J. & Baylin, S. A bird's eye view of global methylation. Nat Genet 24, 101–102 (2000). https://doi.org/10.1038/72730

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