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YAP and the drug resistance highway

Deciphering mechanisms of drug resistance is crucial to winning the battle against cancer. A new study points to an unexpected function of YAP in drug resistance and illuminates its potential role as a therapeutic target.

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Figure 1: Bypassing barriers on the cancer highway.

Marina Corral Spence/Nature Publishing Group

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Acknowledgements

Work in the laboratory of Y.S. is supported by the Israeli Science Foundation (1604/13; 877/13), the European Research Council (StG-335377), and the Knell and Hamburger families.

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Correspondence to Yardena Samuels.

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Keren-Paz, A., Emmanuel, R. & Samuels, Y. YAP and the drug resistance highway. Nat Genet 47, 193–194 (2015). https://doi.org/10.1038/ng.3228

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