Abstract
IN a number of secretory tissues, such as the adrenal medulla1, the pancreatic islets2, the pancreatic acinar cells3 and the salivary acinar cells4, the first step in the activation of the secretory process caused by the physiological stimulant has been suggested to be an increase in membrane permeability resulting in Na+ and/or Ca2+ influx. Only in the salivary acinar cells, however, has it been demonstrated directly that the effective membrane resistance decreases during stimulation5 and it has been reported that acetylcholine (ACh) and pancreozymin markedly increase the membrane resistance in rat pancreatic acinar cells6.
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References
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PETERSEN, O. Mechanism of Action of Pancreozymin and Acetylcholine on Pancreatic Acinar Cells. Nature New Biology 244, 73 (1973). https://doi.org/10.1038/newbio244073a0
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DOI: https://doi.org/10.1038/newbio244073a0
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