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Comparison of Free and 80S RNA-associated RNAs of Mouse L Cell Virions

Nature New Biology volume 243, pages 236–238 (1973)Cite this article

Abstract

PREVIOUS reports on the characterization of virions produced by chronically infected mouse L cells have shown that they are morphologically and biochemically closely related to the RNA tumour viruses1–5. The L cell virion (LCV) is, however, defective in that it does not induce tumours in animals or transform normal mouse cells in vitro2. The nature of the defect might be related to the fact that LCV has been found to have only a negligible DNA polymerase (“reverse transcriptase”) activity5.

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Authors and Affiliations

  1. Department of Microbiology and Immunology, Duke University Medical Center, Durham, North Carolina, 27710

    J. L. NICHOLS & MARIE WADDELL

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  1. J. L. NICHOLS
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  2. MARIE WADDELL
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NICHOLS, J., WADDELL, M. Comparison of Free and 80S RNA-associated RNAs of Mouse L Cell Virions. Nature New Biology 243, 236–238 (1973). https://doi.org/10.1038/newbio243236a0

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  • DOI: https://doi.org/10.1038/newbio243236a0

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