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9-cis Isomerization of all-trans Retinal during in vitro Regeneration of Visual Pigment

Nature New Biology volume 243, pages 185–186 (1973)Cite this article

Abstract

DATA showing that almost complete regeneration of rhodopsin is possible in isolated rod outer segments (ROS) have recently been published1–6. The observation of complete regeneration of visual pigment led to the conclusion that the factor inducing all-trans ⇐ 11-cis isomerization of retinal is present in the saline extracts of retina3–6. We have studied the conditions of formation of visual pigment in the ROS fraction of cattle retina and have shown that in the experimental conditions used the product of regeneration is isorhodopsin.

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Authors and Affiliations

  1. The Laboratory of the Biochemical Bases of Reception, Sechenov Institute of Evolutionary Physiology and Biochemistry, Academy of Sciences of the USSR, Leningrad, 194223, Thorez pr. 52

    I. A. OSTAPENKO & V. V. FURAYEV

Authors
  1. I. A. OSTAPENKO
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  2. V. V. FURAYEV
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OSTAPENKO, I., FURAYEV, V. 9-cis Isomerization of all-trans Retinal during in vitro Regeneration of Visual Pigment. Nature New Biology 243, 185–186 (1973). https://doi.org/10.1038/newbio243185a0

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