Abstract
ACTIVATED factor X (Xa) is a proteolytic enzyme with an active site serine1. In the presence of factor V, calcium ions and phospholipid, it catalyses the conversion of prothrombin to thrombin during blood coagulation2. Factor X is activated in the extrinsic clotting system by a complex of factor VII, tissue factor and calcium ions by limited proteolysis3. A similar product may also be obtained from factor X by the action of the coagulant protein from Russell's viper venom (RVV), and calcium ions4.
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MATTOCK, P., ESNOUF, M. A Form of Bovine Factor X with a Single Polypeptide Chain. Nature New Biology 242, 90–92 (1973). https://doi.org/10.1038/newbio242090a0
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DOI: https://doi.org/10.1038/newbio242090a0
