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Double Helical Complex formed from a Polynucleotide and a Complementary Monomer

Nature New Biology volume 242, pages 45–46 (1973)Cite this article

Abstract

HELICAL complexes between polynucleotides and complementary monomers, in which the polymer provides a linear matrix of binding sites for the monomers, are particularly important for various reasons. Presumably these complexes played a key role in early prebiotic evolution and will provide us with valuable information about enzyme-free recognition and replication. They are also useful for a study of the molecular interactions in helical structures.

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Author information

Author notes

  1. GEOFFREY W. HOFFMAN

    Present address: IBM Research Laboratory, San José, California

  2. ALLEN SENEAR

    Present address: Department of Molecular Biophysics, Yale University, New Haven, Connecticut

Authors and Affiliations

  1. Max Planck Institut für Biophysikalische Chemie, 34, Göttingen

    DIETMAR PÖRSCHKE, GEOFFREY W. HOFFMAN & ALLEN SENEAR

Authors
  1. DIETMAR PÖRSCHKE
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  2. GEOFFREY W. HOFFMAN
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  3. ALLEN SENEAR
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PÖRSCHKE, D., HOFFMAN, G. & SENEAR, A. Double Helical Complex formed from a Polynucleotide and a Complementary Monomer. Nature New Biology 242, 45–46 (1973). https://doi.org/10.1038/newbio242045a0

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  • DOI: https://doi.org/10.1038/newbio242045a0

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