Abstract
THE implantation of animal tissues in diffusion chambers within test animals has been employed in a number of studies1,2 to provide the cells with an environment resembling their natural milieu. It has been reported by Hays1 and by Osoba and Miller2 that some thymus function is preserved when the gland is enclosed in diffusion chambers and implanted in the peritoneal cavity. These workers used isologous systems for culturing the thymuses, implanting the chambers in mice of the same strain as the donor. I show here that when the thymus enclosed in diffusion chambers is implanted in the peritoneal cavity of heterologous animals (mouse thymus in the rabbit), the activity of the gland is preserved.
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References
Hays, E. F., Blood, 29, 29 (1967).
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SPITZ, M. Preservation of Thymus Functionality during in vivo Culture in Heterologous Systems. Nature New Biology 240, 285–286 (1972). https://doi.org/10.1038/newbio240285a0
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DOI: https://doi.org/10.1038/newbio240285a0
