Abstract
THREE concepts have been formulated to explain observed transfer of substances within peripheral nerve axons: (a) bulk axoplasmic flow of the whole axon contents1, (b) axoplasmic streaming—a bidirectional, differential movement of individual cell organelles within the axoplasm2, and (c) bidirectional axonal transport of particulate or soluble materials, thought to involve specific axoplasmic organelles. A slow phase of axonal protein transport moving at 1 mm per day3 has been interpreted by some to be equivalent to bulk axoplasmic flow.
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SPENCER, P. Reappraisal of the Model for “Bulk Axoplasmic Flow”. Nature New Biology 240, 283–285 (1972). https://doi.org/10.1038/newbio240283a0
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DOI: https://doi.org/10.1038/newbio240283a0
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