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Structural Genes of ATP-dependent Deoxyribonuclease of Escherichia coli

Nature New Biology volume 239, pages 14–16 (1972)Cite this article

Abstract

RECOMBINATION-deficient (Rec−) mutants of E. coli express pleiotropic alterations of various phenotypes such as increased ultraviolet light sensitivity, altered patterns of DNA degradation after irradiation, inability to support growth of certain λ phage mutants and many others in addition to reduced recipient ability in mating with Hfr bacteria1. Yet the primary function of any one of the genes responsible for these alterations has not been elucidated. In this paper, the characteristics of recB and recC mutants having temperature-sensitive functions are described. Particular attention is paid to the properties of the ATP-dependent deoxyribonuclease which is known to be missing in recB and recC mutants2–5.

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Authors and Affiliations

  1. Laboratory of Molecular Biology, National Institute of Arthritis, Metabolism and Digestive Diseases, National Institutes of Health, Bethesda, Maryland, 20014

    JUN-ICHI TOMIZAWA

  2. Department of Biology, Faculty of Science, Osaka University, Toyonaka, Osaka, 560

    HIROFUMI OGAWA

Authors
  1. JUN-ICHI TOMIZAWA
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  2. HIROFUMI OGAWA
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TOMIZAWA, JI., OGAWA, H. Structural Genes of ATP-dependent Deoxyribonuclease of Escherichia coli. Nature New Biology 239, 14–16 (1972). https://doi.org/10.1038/newbio239014a0

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  • DOI: https://doi.org/10.1038/newbio239014a0

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