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Ultrastructure of Human C1q Protein

Nature New Biology volume 238, pages 117–118 (1972)Cite this article

Abstract

THE first component (C1) in the complement system may be defined functionally as a macromolecule capable of binding to antigen-antibody complexes and inducing the sequential reactions of this system. C1 consists of three distinct proteins named C1q, C1r and C1s which,in serum, form a macromolecular complex held together by calcium ions1. The C1q protein was first isolated by Müller-Eberhard and Kunkel2 and Taranta et al.3. The ultrastructure of this basic, heat-labile 11S protein is outlined here.

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Authors and Affiliations

  1. Department of Immunology, National Bacteriological Laboratory, 105 21, Stockholm

    S.-E. SVEHAG, L. MANHEM & B. BLOTH

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  1. S.-E. SVEHAG
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  2. L. MANHEM
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  3. B. BLOTH
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SVEHAG, SE., MANHEM, L. & BLOTH, B. Ultrastructure of Human C1q Protein. Nature New Biology 238, 117–118 (1972). https://doi.org/10.1038/newbio238117a0

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