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Selective Toxicity of Rifamycin Derivatives for Leukaemic Human Leucocytes

Nature New Biology volume 236, pages 166–171 (1972)Cite this article

Abstract

Certain rifamycin derivatives have been found to be more toxic for fresh human leukaemic blood cells than for normal blood cells. These particular derivatives also inhibit the reverse transcriptases of both human and viral origin.

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Authors and Affiliations

  1. Laboratory of Tumor Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20014

    R. GRAHAM SMITH, JACQUELINE WHANG-PENG & ROBERT C. GALLO

  2. Viral Leukemia and Lymphoma Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20014

    PAUL LEVINE

  3. Bionetics Research Laboratories, Bethesda, Maryland, 20014

    ROBERT C. TING

Authors
  1. R. GRAHAM SMITH
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  2. JACQUELINE WHANG-PENG
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  3. ROBERT C. GALLO
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  4. PAUL LEVINE
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  5. ROBERT C. TING
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SMITH, R., WHANG-PENG, J., GALLO, R. et al. Selective Toxicity of Rifamycin Derivatives for Leukaemic Human Leucocytes. Nature New Biology 236, 166–171 (1972). https://doi.org/10.1038/newbio236166a0

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  • DOI: https://doi.org/10.1038/newbio236166a0

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