Abstract
IT is generally accepted that all native DNAs, irrespective of their origin, give essentially identical X-ray diffraction patterns characteristic of the A form at high humidities and of the A form at lower humidities1, 2. The purpose of the work described here was an accurate characterization of B-A conformational changes in a range of DNA by infrared dichroism, which seems to be particularly appropriate for the structural characterization of nucleic acids3–6 as a complement of X-ray diffraction. In previous infrared studies the A form and B-A conformational changes were not observed7.
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PILET, J., BRAHMS, J. Dependence of B-A Conformational Change in DNA on Base Composition. Nature New Biology 236, 99–100 (1972). https://doi.org/10.1038/newbio236099a0
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DOI: https://doi.org/10.1038/newbio236099a0
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