Abstract
IT has been reported that medium modified by contact with living cells (conditioned medium) has a favourable effect on cell growth, but the nature of the effector has usually remained obscure. We report here the properties of a growth stimulating factor produced in cultures of human fibroblasts, and show that most of its effect is due to putrescine (diaminobutane).
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POHJANPELTO, P., RAINA, A. Identification of a Growth Factor produced by Human Fibroblasts in vitro as Putrescine. Nature New Biology 235, 247–249 (1972). https://doi.org/10.1038/newbio235247a0
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DOI: https://doi.org/10.1038/newbio235247a0
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