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Identification of a Growth Factor produced by Human Fibroblasts in vitro as Putrescine

Nature New Biology volume 235, pages 247–249 (1972)Cite this article

Abstract

IT has been reported that medium modified by contact with living cells (conditioned medium) has a favourable effect on cell growth, but the nature of the effector has usually remained obscure. We report here the properties of a growth stimulating factor produced in cultures of human fibroblasts, and show that most of its effect is due to putrescine (diaminobutane).

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Authors and Affiliations

  1. Department of Virology, University of Helsinki,

    PIRKKO POHJANPELTO

  2. Department of Medical Chemistry, University of Helsinki,

    A. RAINA

Authors
  1. PIRKKO POHJANPELTO
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  2. A. RAINA
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POHJANPELTO, P., RAINA, A. Identification of a Growth Factor produced by Human Fibroblasts in vitro as Putrescine. Nature New Biology 235, 247–249 (1972). https://doi.org/10.1038/newbio235247a0

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  • DOI: https://doi.org/10.1038/newbio235247a0

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