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Role for Endonuclease I in the Transmission Process of Colicin E2

Abstract

The bactericide colicin E2 is believed to act by binding to surface receptors and thereby initiating the movement of periplasmic endonuclease I to the membrane or cytoplasm, with subsequent DNA degradation. Escherichia coli cells are found to become resistant to colicin E2 by losing their endonuclease I through mutation or osmotic shock treatment.

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ALMENDINGER, R., HAGER, L. Role for Endonuclease I in the Transmission Process of Colicin E2. Nature New Biology 235, 199–203 (1972). https://doi.org/10.1038/newbio235199a0

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  • DOI: https://doi.org/10.1038/newbio235199a0

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