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Bursa of Fabricius as Site of Origin of Germinal Centre Cells

Abstract

GERMINAL centres consist of proliferating lymphoid blast cells arising in follicular areas of lymphoid tissue in response to antigen injection1. These centres have been implicated as sites of origin of memory cells for the secondary immune response2–4 with specificity for the antigen which induced their formation5.

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DURKIN, H., THEIS, G. & THORBECKE, G. Bursa of Fabricius as Site of Origin of Germinal Centre Cells. Nature New Biology 235, 118–119 (1972). https://doi.org/10.1038/newbio235118a0

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