Abstract
DETERMINATION of the frequency of chromosome aberrations in cultured blood lymphocytes may provide a means of measuring ionizing radiation doses, at least after whole body exposure. Much work has been done with human blood irradiated in vitro1,2, but before these results can be applied to radiation exposure in vivo, the difference between in vitro and in vivo exposure must be shown to be quantitatively negligible.
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References
United Nations Scientific Committee on the Effects of Atomic Radiation (Twenty-Fourth Session, Supplement No. 13 (A/7613), New York, 1969).
Evans, H. J., Intern. Atomic Energy Agency Symp. on New Developments in Physical and Biological Radiation Detectors (1970).
Buckton, K. E., Langlands, A. O., Smith, P. G., Woodcock, G. E., and Looby, P. C., Intern. J. Radiat. Biol., 4, 369 (1971).
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CLEMENGER, J., SCOTT, D. In vitro and in vivo Sensitivity of Cultured Blood Lymphocytes to Radiation Induction of Chromosome Aberrations. Nature New Biology 234, 154 (1971). https://doi.org/10.1038/newbio234154a0
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DOI: https://doi.org/10.1038/newbio234154a0