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Selective Inhibition of Transformed Cells in Culture by Anti-thymidine Antibodies

Nature New Biology volume 234, pages 127–128 (1971)Cite this article

Abstract

ANTIBODIES specific for each of the five common bases of DNA and RNA and various dinucleoside phosphates have been induced in rabbits following immunization with nucleoside-protein conjugates1–3. These antibodies react with denatured or single stranded DNA to fix complement, to precipitate the DNA and to inhibit its in vitro priming activity4, although they have no reaction with native DNA.

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Author information

Authors and Affiliations

  1. Department of Microbiology, College of Physicians and Surgeons, Columbia University, New York, NY 10032

    D. S. P. LIEBESKIND, K. C. HSU, B. F. ERLANGER & S. M. BEISER

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  1. D. S. P. LIEBESKIND
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  2. K. C. HSU
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  3. B. F. ERLANGER
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  4. S. M. BEISER
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LIEBESKIND, D., HSU, K., ERLANGER, B. et al. Selective Inhibition of Transformed Cells in Culture by Anti-thymidine Antibodies. Nature New Biology 234, 127–128 (1971). https://doi.org/10.1038/newbio234127a0

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  • DOI: https://doi.org/10.1038/newbio234127a0

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