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Origin of PHA-responsive Cells in the Mouse Thymus after Treatment of the Animal with Hydrocortisone

Abstract

AFTER treatment of mice with corticosteroids, the number of cells in the thymus is greatly reduced. However, on a cell to cell basis, these cells are more competent to cause graft versus host reactions, and to cooperate with ? cells in antibody responses, than are thymus cells from normal animals1–6. We are primarily concerned here with the origin of the corticosteroid resistant cells.

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References

  1. Blomgren, H., and Andersson, B., Exp. Cell Res., 57, 185 (1969).

    Article  CAS  Google Scholar 

  2. Andersson, B., and Blomgren, H., Cell. Immunol., 1, 362 (1970).

    Article  CAS  Google Scholar 

  3. Blomgren, H., Clin. Exp. Immunol., 8, 279 (1971).

    CAS  PubMed  PubMed Central  Google Scholar 

  4. Leckband, E., Fed. Proc., 29, 621 (1970).

    Google Scholar 

  5. Cohen, J. J., and Claman, H. N., J. Exp. Med., 133, 1026 (1971).

    Article  CAS  Google Scholar 

  6. Cohen, J. J., Fishbach, M., and Claman, H. N., J. Immunol., 105, 1146 (1970).

    CAS  PubMed  Google Scholar 

  7. Davies, A. J. S., Leuchars, E., Wallis, V. J., and Koller, P. C., Transplantation, 4, 438 (1966).

    Article  CAS  Google Scholar 

  8. Leuchars, E., Morgan, A., Davies, A. J. S., and Wallis, V. J., Nature, 214, 801 (1967).

    Article  CAS  Google Scholar 

  9. Festenstein, H., Lancet, i, 182 (1968).

    Article  Google Scholar 

  10. Doenhoff, M. J., Clin. Exp. Immunol., 8, 603 (1971).

    CAS  PubMed  PubMed Central  Google Scholar 

  11. Ford, C. E., in Tissue Grafting and Radiation, 197 (Academic Press, New York and London, 1966).

    Google Scholar 

  12. Raff, M. C., and Owen, J. J. T., in Morphological and Functional Aspects of Immunity, 11 (Plenum Press, New York and London, 1971).

    Book  Google Scholar 

  13. Raff, M. C., Transplant. Rev., 6, 52 (1971).

    CAS  PubMed  Google Scholar 

  14. Weber, W. T., J. Cell Physiol., 67, 285 (1966).

    Article  CAS  Google Scholar 

  15. Weber, W. T., J. Cell Physiol., 68, 117 (1966).

    Article  CAS  Google Scholar 

  16. Warner, N. L., Aust. J. Exp. Biol. Med. Sci., 42, 401 (1964).

    Article  CAS  Google Scholar 

  17. Borum, K., Scand. J. Haemat., 5, 339 (1968).

    Article  CAS  Google Scholar 

Download references

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ELLIOTT, E., WALLIS, V. & DAVIES, A. Origin of PHA-responsive Cells in the Mouse Thymus after Treatment of the Animal with Hydrocortisone. Nature New Biology 234, 77–78 (1971). https://doi.org/10.1038/newbio234077a0

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