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On the Mechanism of Action of lac Repressor

Abstract

Chen et al. have proved conclusively that lac repressor and RNA polymerase bind independently to wild type lac DNA in vitro. To explain the lac ps mutation, which causes competitive binding between repressor and polymerase, they suggest that a new promoter site has been created near the lac operator.

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CHEN, B., DE CROMBRUGGHE, B., ANDERSON, W. et al. On the Mechanism of Action of lac Repressor. Nature New Biology 233, 67–70 (1971). https://doi.org/10.1038/newbio233067a0

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