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Phosphoglycerate Kinase Polymorphism in Kangaroos provides Further Evidence for Paternal X Inactivation

Nature New Biology volume 230, pages 155–157 (1971)Cite this article

Abstract

REDUCED activity of the glycolytic enzyme phosphoglycerate kinase (EC 2723 : ATP : 3 phospho-D-glycerate 1 phosphotransferase, PGK) is associated with hereditary haemolytic anaemia1–3. A family study suggests that the gene involved is sex linked. Beutler has described a starch gel technique for electrophoresing and detecting the human erythrocytic enzyme4. He examined Caucasian, Negro and Oriental blood donors and found no variants. We have surveyed several hundred erythrocyte samples from a number of species of kangaroos (Macropodidae) using his technique.

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Authors and Affiliations

  1. Department of Genetics and Human Variation, La Trobe University, Bundoora, Victoria

    D. W. COOPER & J. L. VANDEBERG

  2. School of Biological Sciences, Macquarie University, North Ryde, NSW

    G. B. SHARMAN

  3. CSIRO Division of Wildlife Research, PO Box 109, Canberra City

    W. E. POOLE

Authors
  1. D. W. COOPER
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  2. J. L. VANDEBERG
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  3. G. B. SHARMAN
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  4. W. E. POOLE
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COOPER, D., VANDEBERG, J., SHARMAN, G. et al. Phosphoglycerate Kinase Polymorphism in Kangaroos provides Further Evidence for Paternal X Inactivation. Nature New Biology 230, 155–157 (1971). https://doi.org/10.1038/newbio230155a0

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