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Direct Determination of the Superhelix Density of Closed Circular DNA by Viscometric Titration

Nature New Biology volume 229, pages 10–13 (1971)Cite this article

Abstract

A method has been developed for determining directly the superhelix density of DNA; this is more sensitive and subject to fewer constraints than sedimentation analysis.

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Authors and Affiliations

  1. Division of Biology and Chemistry and Chemical Engineering, Norman W. church Laboratory of Chemical Biology, California liititute of Technology, 120, East California Boulevard, Pasadena, California, 91109

    BERNARD M. J. RÉVET, MAURICE SCHMIR & JEROME VINOGRAD

Authors
  1. BERNARD M. J. RÉVET
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  2. MAURICE SCHMIR
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  3. JEROME VINOGRAD
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RÉVET, B., SCHMIR, M. & VINOGRAD, J. Direct Determination of the Superhelix Density of Closed Circular DNA by Viscometric Titration. Nature New Biology 229, 10–13 (1971). https://doi.org/10.1038/newbio229010a0

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