Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Practice Point
  • Published:

What is the role of radiation dose escalation in the treatment of localized prostate cancer?

Nature Clinical Practice Urology volume 5, pages 418–419 (2008)Cite this article

Kuban DA et al. (2008) Long-term results of the M.D. Anderson randomized dose-escalation trial for prostate cancer. Int J Radiat Oncol Biol Phys 70: 67–74

Background

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Pollack A et al. (2000) Preliminary results of a randomized radiotherapy dose-escalation study comparing 70 Gy to 78 Gy for prostate cancer. J Clin Oncol 18: 3904–3011

    Article  CAS  Google Scholar 

  2. Zietman AL et al. (2005) Comparison of conventional-dose vs high dose conformal therapy in clinically localized adenocarcinoma of the prostate. JAMA 294: 1233–1239

    Article  CAS  Google Scholar 

  3. Peeters STH et al. (2006) Dose-response in radiotherapy for localized prostate cancer: results of the Dutch multicenter randomized phase III trial comparing 68 Gy of radiotherapy with 78 Gy. J Clin Oncol 24: 1990–1996

    Article  Google Scholar 

  4. Dearnaley DP et al. (2007) Escalated-dose versus standard-dose conformal radiotherapy in prostate cancer: first results from the MRC RT01 randomized controlled trial. Lancet Oncol 8: 475–487

    Article  Google Scholar 

  5. D'Amico A et al. (2008) Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial. JAMA 299: 289–295

    CAS  PubMed  Google Scholar 

Download references

Acknowledgements

The synopsis was written by Nick Groves-Kirkby, Associate Editor, Nature Clinical Practice.

Author information

Author notes

  1. Centre Hospitalier, Universitaire de Grenoble, Department of Radiotherapy, BP 217X, Grenoble, Cedex F-38043, France mbolla@chu-grenoble.fr

Authors and Affiliations

  1. M Bolla is Head of the Department of Radiation Oncology, Joseph Fourier University, Hôpital Albert Michallon, Grenoble, France.,

    Michel Bolla

Authors
  1. Michel Bolla
    View author publications

    You can also search for this author in PubMed Google Scholar

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bolla, M. What is the role of radiation dose escalation in the treatment of localized prostate cancer?. Nat Rev Urol 5, 418–419 (2008). https://doi.org/10.1038/ncpuro1153

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncpuro1153

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing