Abstract
A cohort study of 1,669 patients with stage 3 or 4 chronic kidney disease (CKD) was conducted by Elsayed et al. to assess waist:hip ratio and BMI as risk factors for myocardial infarction or fatal coronary heart disease; data were drawn from two community studies (the Atherosclerosis Risk in Communities Study and the Cardiovascular Health Study). The cohort study showed that waist:hip ratio, but not BMI, is associated with cardiac events in patients with moderate CKD. This Practice Point commentary highlights the issues to consider when interpreting and generalizing these results, including the potentially confounding effects of metabolic syndrome and the lack of measurement of albuminuria, the main nontraditional cardiovascular risk factor in CKD.
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De Nicola, L., Conte, G. Waist:hip ratio is a better predictor of cardiovascular risk than BMI in patients with moderate CKD. Nat Rev Nephrol 4, 592–593 (2008). https://doi.org/10.1038/ncpneph0927
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DOI: https://doi.org/10.1038/ncpneph0927
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Association of two common polymorphisms of apolipoprotein A5 gene with metabolic syndrome indicators in a North Iranian population, a cross-sectional study
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