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Upper gastrointestinal bleeding in a patient with AIDS

Nature Clinical Practice Gastroenterology & Hepatology volume 3, pages 349–353 (2006)Cite this article

Abstract

Background A 38-year-old man with AIDS and hepatitis C was admitted to our hospital in January 2005, with complaints of epigastric pain, odynophagia, and melena of 4 days' duration. The patient was not taking highly active antiretroviral therapy because of poor compliance and he denied use of NSAIDs.

Investigations Physical examination, stool guaiac test, laboratory investigations, and esophagogastroduodenoscopy with biopsies of gastric ulcerations.

Diagnosis Non-Hodgkin's lymphoma of the stomach (diffuse large B-cell type) with associated gastric ulceration and bleeding.

Management Injection of epinephrine and bipolar coagulation for the bleeding malignant ulcer, and PPI therapy.

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Figure 1: Endoscopic image of the gastric body of a 38-year-old male with AIDS.
Figure 2: Causes of acute upper gastrointestinal hemorrhage in patients with HIV infection.

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Authors and Affiliations

  1. second-year Internal Medicine Resident at the University of Texas Southwestern Medical Center,

    Valeska Balderas & Stuart Jon Spechler

  2. Chief of the Division of Gastroenterology at the Dallas VA Medical Center, Professor of Medicine, and Holder of the Berta M and Cecil O Patterson Chair in Gastroenterology at The University of Texas Southwestern Medical Center, Dallas, TX, USA

    Valeska Balderas & Stuart Jon Spechler

Authors
  1. Valeska Balderas
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  2. Stuart Jon Spechler
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Corresponding author

Correspondence to Stuart Jon Spechler.

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Competing interests

Dr Spechler is on the Speaker's Bureau for AstraZenica, TAP and Janssen, and receives Grant Support from AstraZenica.

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Balderas, V., Jon Spechler, S. Upper gastrointestinal bleeding in a patient with AIDS. Nat Rev Gastroenterol Hepatol 3, 349–353 (2006). https://doi.org/10.1038/ncpgasthep0497

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