New advances in mass spectrometry allow researchers to determine the way multiple protein subunits are assembled spatially. This approach can reveal topology and provide information on the interacting proteins of the 19S proteasome.
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Leary, J. How complex is a complex?. Nat Chem Biol 2, 515–516 (2006). https://doi.org/10.1038/nchembio1006-515
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DOI: https://doi.org/10.1038/nchembio1006-515