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Supramolecular catalysis

Terpenes in tight spaces

Nature Chemistry volume 7, pages 187–189 (2015)Cite this article

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The ability of enzymes to direct the synthesis of complex natural products from simple starting materials is epitomized by terpene biosynthesis. Now, a supramolecular catalyst has been shown to mimic some of the reactivity of this process.

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Figure 1: Non-stop polycyclization/rearrangement controlled by terpene cyclase enzymes.
Figure 2: Supramolecular tail-to-head cyclization.

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Authors and Affiliations

  1. Jeremy Roach and Ryan Shenvi are in the Department of Chemistry at the Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA,

    Jeremy J. Roach & Ryan A. Shenvi

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  1. Jeremy J. Roach
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  2. Ryan A. Shenvi
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Correspondence to Ryan A. Shenvi.

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Roach, J., Shenvi, R. Terpenes in tight spaces. Nature Chem 7, 187–189 (2015). https://doi.org/10.1038/nchem.2191

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