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Natural product biosynthesis

The road to L

A combined experimental and theoretical study of the biosynthesis of a family of antibacterial natural products has uncovered some of the finer details of unusual stereoselectivity observed in a peptide cyclization.

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Figure 1: Lanthionine peptide biosynthesis.

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Correspondence to Romas J. Kazlauskas.

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Jones, B., Kazlauskas, R. The road to L. Nature Chem 7, 11–12 (2015). https://doi.org/10.1038/nchem.2137

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