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Organizing cytoplasmic microtubules: no nucleus, no problem

Correct organization of a polarised microtubule array is vital for eukaryotic cells. Microtubule organizing centers (MTOCs) are generally believed to have an essential role in this process. However, two papers published in this issue have demonstrated that in fission yeast, interphase microtubules can self-organize in anucleate cells lacking any authentic MTOC.

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Figure 1: Microtubule organizing centers in fission yeast and generation of anucleate cells.
Figure 2: Schematic representation of microtubule organization of a normal cell and an anucleate cell.

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Horio, T., Toda, T. Organizing cytoplasmic microtubules: no nucleus, no problem. Nat Cell Biol 8, 1041–1043 (2006). https://doi.org/10.1038/ncb1006-1041

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