Abstract
The cargo-binding tail of the motor protein kinesin acts as a regulator of kinesin-driven vesicle transport. In the absence of bound cargo, the kinesin tail interacts with the motor domains and inhibits their activity. Cargo binding blocks this interaction and relieves the inhibition.
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Cross, R., Scholey, J. Kinesin: the tail unfolds. Nat Cell Biol 1, E119–E121 (1999). https://doi.org/10.1038/12947
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DOI: https://doi.org/10.1038/12947
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