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Double JMY: making actin fast

Nature Cell Biology volume 11, pages 375–376 (2009)Cite this article

The assembly of actin networks is dependent on nucleation-promoting factors. A new study identifies JMY as a protein containing two separate nucleation-promoting activities that shuttles between the nucleus and the cytoplasm and promotes cell migration. These observations indicate that JMY is an important factor controlling actin dynamics in motile cells.

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Figure 1: JMY functions both in and out of the nucleus.

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Authors and Affiliations

  1. David W. Roadcap and James E. Bear are at the Lineberger Comprehensive Cancer Center and Department of Cell & Developmental Biology, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina 27599, USA. jbear@email.unc.edu,

    David W. Roadcap & James E. Bear

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  1. David W. Roadcap
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  2. James E. Bear
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Roadcap, D., Bear, J. Double JMY: making actin fast. Nat Cell Biol 11, 375–376 (2009). https://doi.org/10.1038/ncb0409-375

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