Cajal described the neural synapse as a “protoplasmic kiss”, and this metaphor applies equally well to the immunological synapse. Viruses are masters at co-opting the machinery of the immune response and, remarkably, the retrovirus HTLV-1 (human T lymphotrophic virus 1) seems to use an immunological-synapse-like structure to conceal viral spread.
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Dustin, M. Viral spread through protoplasmic kiss. Nat Cell Biol 5, 271–272 (2003). https://doi.org/10.1038/ncb0403-271
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DOI: https://doi.org/10.1038/ncb0403-271
