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A crossbridge too far

Nature Cell Biology volume 4, pages E8–E10 (2002)Cite this article

Myosin V is a marvellous molecular motor that delivers various cargo to specific addresses in eukaryotic cells. Recent developments are leading to a detailed molecular understanding of how this enzyme transduces the chemical energy of ATP hydrolysis into mechanical movement along actin filaments.

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Figure 1
Figure 2: Two current working hypotheses for nucleotide-dependent coupling of myosin V stepping.

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Authors and Affiliations

  1. Department of Biochemistry, Stanford University School of Medicine, Stanford, 94305, California, USA

    James A. Spudich & Ronald S. Rock

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  1. James A. Spudich
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  2. Ronald S. Rock
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Spudich, J., Rock, R. A crossbridge too far. Nat Cell Biol 4, E8–E10 (2002). https://doi.org/10.1038/ncb0102-e8

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