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Cell polarity: the PARty expands

Nature Cell Biology volume 3, pages E7–E9 (2001)Cite this article

Recent work has revealed an evolutionarily conserved trio of proteins that regulate cell polarity in epithelial cells, embryonic blastomeres and neural precursors. This common cell-polarity mechanism is used in cell-specific ways, as highlighted by the recent finding that at least two different types of asymmetric division are observed in Drosophila neural precursors.

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Figure 1: The PAR-3–PAR-6–aPKC protein complex.
Figure 2: Two types of asymmetric division in the Drosophila cell lineage for external sense organs.

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  1. the Institute of Molecular Biology and the Institute of Neuroscience, HHMI, University of Oregon, Eugene, 97403, Oregon, USA

    Chris Q. Doe

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  1. Chris Q. Doe
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Doe, C. Cell polarity: the PARty expands. Nat Cell Biol 3, E7–E9 (2001). https://doi.org/10.1038/35050684

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