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Racing lipid rafts for synaptic-vesicle formation

Abstract

A new screen for proteins that bind cholesterol in vivo has identified synaptophysin I. This protein’s cholesterol-binding ability may be of key importance in the generation of synaptic vesicles at plasma membranes.

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Figure 1: Exocytosis and endocytosis of synaptic vesicles.

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Martin, T. Racing lipid rafts for synaptic-vesicle formation. Nat Cell Biol 2, E9–E11 (2000). https://doi.org/10.1038/71392

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