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Cloning by numbers

A new technique in mouse cloning leads to dramatically higher birthrates.

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Figure 1: Effect of clone aggregation on embryo development.

References

  1. Boiani, M., Eckardt, S., Leu, N.A, Schöler, H.R. & McLaughlin, K.J. EMBO J. 22, 5304–5312 (2003).

    Article  CAS  Google Scholar 

  2. Rideout, W.N., III, Eggan, K. & Jaenisch, R. Science 293, 1093–1098 (2001).

    Article  CAS  Google Scholar 

  3. Boiani, M., Eckardt, S., Schöler, H.R. & McLaughlin, K.J. Genes Dev. 16, 1209–1219 (2002).

    Article  CAS  Google Scholar 

  4. Dean, W. et al. Proc. Natl. Acad. Sci., USA 98, 13734–13738 (2001).

    Article  CAS  Google Scholar 

  5. Koo, D.B. et al. Biol. Reprod. 67, 487–492 (2002).

    Article  CAS  Google Scholar 

  6. Koo, D.B. et al. Biol. Reprod. 63, 986–992. (2000).

    Article  CAS  Google Scholar 

  7. Chesne, P. et al. Nat. Biotechnol. 20, 366–369 (2002).

    Article  CAS  Google Scholar 

  8. Chung, Y.G., Mann, M.R., Bartolomei, M.S. & Latham, K.E. Biol. Reprod. 66, 1178–1184 (2002).

    Article  CAS  Google Scholar 

  9. Goodall, H. & Johnson, M.H. J. Embryol. Exp. Morphol. 79, 53–76 (1984).

    CAS  PubMed  Google Scholar 

  10. Burnside, A.S. & Collas, P. Eur. J. Cell Biol. 81, 585–591 (2002).

    Article  CAS  Google Scholar 

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Houdebine, LM. Cloning by numbers. Nat Biotechnol 21, 1451–1452 (2003). https://doi.org/10.1038/nbt1203-1451

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