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Oxidoreductase Enzymes in Biotechnology: Current Status and Future Potential

Bio/Technology volume 1, pages 677–686 (1983)Cite this article

Abstract

The variety of chemical transformations catalyzed by enzymes make these catalysts a prime target for exploitation by the emerging biotechnology industries. Over the last two decades, intense research in the area of enzyme technology has provided many approaches that facilitate the practical application of enzymes. This review focuses on oxidoreductases, the large class of enzymes catalyzing biological oxidation/reduction reactions. Since so much industrial chemistry involves oxidation/reduction processes, the use of oxidoreductases to carry out synthetic transformations is a major area of interest. Of particular significance in this regard are oxidoreductase–mediated asymmetric syntheses of amino acids, steroids, and other pharmaceuticals, and of a host of specialty chemicals. Another area of major importance is the current extensive use of oxidoreductases in clinical diagnosis and other analytical applications. Future applications for oxidoreductases can be visualized in areas as diverse as polymer synthesis, pollution control, and oxygenation of hydrocarbons.

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  1. School of Chemistry, Georgia Institute of Technology, Atlanta, Georgia, 30332

    Sheldon W. May & Stephen R. Padgette

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May, S., Padgette, S. Oxidoreductase Enzymes in Biotechnology: Current Status and Future Potential. Nat Biotechnol 1, 677–686 (1983). https://doi.org/10.1038/nbt1083-677

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