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Gene therapy gets the Beauty treatment

Nature Biotechnology volume 20, pages 987–988 (2002)Cite this article

Gene-deleted adenovirus vectors modified to carry the Sleeping Beauty transposon machinery achieve long-term transgene stabilization and expression.

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Figure 1: The use of a transgene-expressing Sleeping Beauty transposon together with the necessary recombinases allows integration.

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Authors and Affiliations

  1. associate professor at the Carl C. Icahn Institute for Gene Therapy and Molecular Medicine and the Department of Microbiology, Mount Sinai School of Medicine, New York, 10029, NY

    R. Michael Linden

  2. He is funded by the National Institutes of Health and by PrimeBioTech, Paris, France

    R. Michael Linden

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  1. R. Michael Linden
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Linden, R. Gene therapy gets the Beauty treatment. Nat Biotechnol 20, 987–988 (2002). https://doi.org/10.1038/nbt1002-987

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