Sperm cells derived from embryonic stem cells give rise to mice with genetic imprinting defects.
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Lucifero, D., Reik, W. Artificial sperm and epigenetic reprogramming. Nat Biotechnol 24, 1097–1098 (2006). https://doi.org/10.1038/nbt0906-1097
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DOI: https://doi.org/10.1038/nbt0906-1097