Whitcombe et al. (p. 804) describe a new method for detecting amplicons in high-throughput PCR reactions, using specially designed fluorescent molecules that function both as PCR primers and as probes for amplicons. The unique unimolecular design of this system could potentially give it an edge over existing bimolecular systems.
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DeWitt, N. Unimolecular diagnostics. Nat Biotechnol 17, 739 (1999). https://doi.org/10.1038/11649
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DOI: https://doi.org/10.1038/11649