Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Towards universal red blood cells

Nature Biotechnology volume 25, pages 427–428 (2007)Cite this article

Novel glycosidases convert group A and B red blood cells to universal group O cells.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Group O red cells are called 'universal' because they are suitable for transfusion to individuals of all ABO groups.

Katie Ris

References

  1. Liu, Q.P. et al. Nat. Biotechnol. 25, 454–464 (2007).

    Article  CAS  Google Scholar 

  2. Goldstein, J. Transfus. Med. Rev. 3, 206–212 (1989).

    Article  CAS  Google Scholar 

  3. Kruskall, M.S. et al. Transfusion 40, 1290–1298 (2000).

    Article  CAS  Google Scholar 

  4. Hoskins, L.C. et al. Transfusion 35, 813–821 (1995).

    Article  CAS  Google Scholar 

  5. Rajan, S.S. et al. Structure 12, 1619–1629 (2004).

    Article  CAS  Google Scholar 

  6. Yip, V.L. et al. J. Am. Chem. Soc. 126, 8354–8355 (2004).

    Article  CAS  Google Scholar 

  7. Yip, V.L.Y. & Withers, S.G. Org. Biomol. Chem. 2, 2707–2713 (2004).

    Article  CAS  Google Scholar 

  8. Withers, S.G. Carbohydrate Polymers 44, 325–337 (2001).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Geoff Daniels is at the Bristol Institute for Transfusion Sciences, NHSBT, Bristol, UK. geoff.daniels@nbs.nhs.uk,

    Geoff Daniels

  2. Stephen G. Withers is at the University of British Columbia, Canada. withers@chem.ubc.ca,

    Stephen G Withers

Authors
  1. Geoff Daniels
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Stephen G Withers
    View author publications

    You can also search for this author in PubMed Google Scholar

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Daniels, G., Withers, S. Towards universal red blood cells. Nat Biotechnol 25, 427–428 (2007). https://doi.org/10.1038/nbt0407-427

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt0407-427

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing