Two new methods offer different means to probe protein–DNA interactions.
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References
Heyduk, T. & Heyduk, E. Nat. Biotechnol. 20, 171–176 (2002).
Storek, M.J., Ernst, A. & Verdine, G.L. Nat. Biotechnol. 20, 183–186 (2002).
Hill, J.J. & Royer, C.A. Methods Enzymol. 278, 390–416 (1997).
Liu, P.Q. et al. J. Biol. Chem. 276, 11323–11334 (2001).
Mapp, A.K., Ansari, A.Z., Ptashne, M. & Dervan, P.B. Proc. Nat. Acad. Sci. USA 97, 3930–3935 (2000).
Wissmann, A. & Hillen, W. Methods Enzymol. 208, 365–379 (1991)
Min, C., Cushing, T.D. & Verdine, G.L. J. Am. Chem. Soc. 118, 6116–6120 (1996).
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Jantz, D., Berg, J. Binding assays get into the groove. Nat Biotechnol 20, 126–127 (2002). https://doi.org/10.1038/nbt0202-126
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DOI: https://doi.org/10.1038/nbt0202-126