Abstract
Rodent bioassays often require fresh, uncontaminated urine from a large number of mice. The authors describe a quick and simple method to collect moderate to large amounts of urine from individual mice using disposable plastic trays.
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References
Externest, D., Meckelein, B., Schmidt, M.A. & Frey, A. Correlations between antibody immune responses at different mucosal effector sites are controlled by antigen type and dosage. Infect. Immun. 68, 3830–3839 (2000).
Kurien, B.T. & Scofield, R.H. Mouse urine collection using clear plastic wrap. Lab. Anim. 33, 83–86 (1999).
Smith, C.R., Felton, J.S. & Taylor, R.T. Description of a disposable individual-mouse urine collection apparatus. Lab. Anim. Sci. 31, 80–82 (1981).
West, R.W., Stanley, J.W. & Newport, G.D. Single-mouse urine collection and pH monitoring system. Lab. Anim. Sci. 28, 343–345 (1978).
Khosho, F.K., Kaufmann, R.C. & Amankwah, K.S. A simple and efficient method for obtaining urine samples from rats. Lab. Anim. Sci. 35, 513–514 (1985).
Hayashi, S. & Sakaguchi, T. Capillary tube urinalysis for small animals. Lab. Anim. Sci. 25(6), 781–782 (1975).
Fenske, M. Application of a new, simple method for quantitative collection of 24-hour urines in small laboratory animals: determination of basal excretion of proteins, creatinine, urea, electrolytes, and of free steroids. Z.Versuchstierkd. 32, 65–70 (1989).
Perissin, L., Zorzet, S., Rapozzi, V. & Giraldi, T. A non-invasive simple method for measurement of urinary excretion of melatonin in undisturbed mice. J. Pineal Res. 15, 138–140 (1993).
Acknowledgements
We would like to thank A*STAR (R-178-000-010-303), Republic of Singapore for funding as well as Lim Lay Hong and Lim Wei Seng for reading the manuscript.
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Chew, J., Chua, K. Collection of Mouse Urine for Bioassays. Lab Anim 32, 48–50 (2003). https://doi.org/10.1038/laban0803-48
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DOI: https://doi.org/10.1038/laban0803-48
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